A device that filters cancer cells from human blood using sound could help to identify tumour cells that have spread.
Finding tumour cells in the blood indicates a cancer has metastasised – but the molecular markers that are used to identify the cells can modify them and make them unsuitable for studying how treatment is proceeding and for performing basic cancer research.
So Itziar González at the Institute for Acoustics in Madrid, Spain, and colleagues developed an alternative: a tiny vibrating plastic chamber through which a blood sample flows. The vibrations create a standing wave that deflects cells in the blood to a different degree depending on their size. Tumour cells are often larger than blood cells and so collect in a different region of the device. The process does not alter the cells. Continue reading
Monitoring a wound as it heals should get easier thanks to a new kind of optical fiber that could become a part of everyday bandages. The fiber’s coating alters in color in response to changes in acidity, a key health indicator in wounds. The core of the fiber carries light to and from an attached device, which caregivers could use to monitor a wound in real time, says Bastien Schyrr, a Ph.D. student in biomedical engineering at the University of Fribourg, in Switzerland, who last month presented results of a laboratory trial in which the enhanced bandage detected acidity changes in a solution containing human serum. Continue reading
Coaches admire athletes for showing a lot of heart, and poets praise the organ’s passions, but engineers see the human cardiovascular system otherwise. The heart is a pump in a prime location, brimming with energy for the taking, says biomedical engineer Alois Pfenniger. So together with colleagues at the University of Bern and the Bern University of Applied Sciences, in Switzerland, Pfenniger has tested small turbines designed to fit inside a human artery, like an implantable hydroelectric generator. Continue reading