Category Archives: Outlets

Caves of Ice: The Next Frontier in Paleoclimatology?

It’s early June in the Austrian Alps. Tourists in shorts sweat their way up a trail from the cable car above Lake Hallstatt. But the summer heat doesn’t stop a group of scientists from pulling on brightly colored jumpsuits over their hiking clothes at the entrance to Mammuthohle, one of the many limestone caves that riddle the Dachstein Massif. Lukas Plan, a geophysicist at the University of Vienna, straps on his headlamp and pauses to warn the crowd of researchers about the cave they are about to enter. It won’t just be chilly inside, he cautions; it will be an Alpine meat locker.

The crowd, part of the fourth international ice cave workshop organized by a network of European geophysicists and glaciologists, is gathered to visit the cave’s year-round ice formations.

Plan turns toward the tunnel in the mountainside and opens the metal door. A rush of wind bursts out. The group prepares to enter, hoping to read the history of the region’s climate in the cave’s ice.

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Peruvian biologist’s defamation conviction overturned

A defamation case that hinges on a dispute over the presence of genetic modification in Peruvian maize crops, and that has attracted international attention, has moved back to square one — with a twist.

Biologist Ernesto Bustamante Donayre was last April found guilty of defamation — a criminal offence in Peru — for publicly criticizing a report published by a fellow biologist. Last month, however, the conviction was overturned: the appeal judge found that a lower court had not demonstrated that Bustamante had sufficient motivation to harm or defame his alleged victim. A recent government study of the crops in question may shape the outcome of any subsequent proceedings, Bustamante says.

The case began in 2008, when Antonietta Ornella Gutiérrez Rosati of La Molina National Agricultural University in Lima accused Bustamante, the scientific director of private genetic-screening firm BioGenómica, of defaming her by publicly criticizing a study she wrote and publicized that reported evidence of transgenic maize in Peru. Peru does not yet have regulations to control or permit the growing of genetically modified crops, and their illegal introduction is a source of lively debate — in which Bustamante has participated — in the Peruvian media.

In late 2007, Gutiérrez informed a government agency and a newspaper that she had found a P34S promoter and the transgenes NK603 and BT11 in 14 out of 42 maize samples collected from plots in the valley of Barranca, some 200 kilometres north of Lima. Bustamante responded with an opinion article in Peruvian newspaper El Comercio that called the report’s conclusions “absurdly improbable” and based on “gross procedural errors”. He also gave radio interviews and challenged Gutiérrez to submit her report for peer review.

Gutiérrez took Bustamante to court, and in April 2010 a judge found him guilty of defamation, ordering him to pay a fine of 5,000 soles (US$1,800) and placing restrictions on his travel. In 2009, Gutiérrez also presented her paper at a conference of the Peruvian Genetics Society in Cuzco, of which she was then president.

More than 650 scientists from around the world signed a public petition over the case, among them Bustamante’s graduate instructor, Nobel laureate Hamilton Smith of Johns Hopkins University in Baltimore, Maryland, who wrote, “We trained him to be critical of his work, and that of others, and to always seek the truth … It seems almost unimaginable to hear of his legal troubles for simply practicing good science.”

Commenting on the latest judgement, Ricardo Fujita Alarcón, a geneticist at the University of San Martín de Porres in Lima and a member of PeruBiotec, a pro-biotechnology group of which Bustamante is also a member, says, “This will have a positive effect because it shows people you can’t coerce scientists using judicial means.”

Round two

Last month’s overruling directs both parties to return to a conciliation meeting, but does not prevent Gutiérrez bringing a renewed suit in a different lower court, which is allowable under Peruvian law. “If he’s prosecuted again the whole thing would go back to the way it was,” says biochemist Paul Englund, also of Johns Hopkins University, a colleague of Bustamante’s. Englund says he fears that Bustamante’s conviction stifled scientific debate. “He’s someone that speaks his mind honestly, based on data. It’s outrageous that he’s being criminally prosecuted for it,” he adds.

Gutiérrez, who did not respond to an interview request, may still take the suit to another lower court, although the appeals judge recommended that the case go to a pre-trial conciliation hearing first. According to Bustamante, he now stands a better chance of getting a favourable outcome because, since his conviction, the National Institute for Agrarian Innovation (INIA) in Lima has tried to replicate Gutiérrez’s findings in Barranca but has failed to find genetically modified varieties of native maize, despite examining 162 samples.

“In the conciliation hearing I’ll most likely use that as a proof that what I said at that time was later found to be actually true,” Bustamante says. A finding in his favour will discourage other scientists from taking each other to court, Bustamante adds. “It would have been nice to have a judge come out and say, ‘Yes, science should not be taken to court’, but that’s not for lawyers to say. That’s for us scientists to state and to express and to fight for.”

First published by Nature [html] [pdf].
See also a previous story on this case for Nature Biotechnology: [html] [pdf].

Big science at the table

José Ordovas sips a mint tea in a languid café in Madrid, Spain. His eyes scan two mobile phones as he confirms his next appointments. In conversation, he switches effortlessly between Spanish and English to find the right expressions. If the geneticist seems to be moving on a different wavelength from the other patrons, he could blame it on the jet lag: he has just flown from Boston where it’s now 5am. This is his third overseas trip this month, but Ordovas contends his frequent visits from Tufts University, where he’s based, to Europe have no adverse effects. “For me the time difference doesn’t matter, I’m up at 4am to make calls to Europe when I’m home anyway, and then I’m up late on calls to California,” he says.

Ordovas embodies the hustle and bustle of the ‘big science’ approach that has changed nutrition research in the past decade. This field, once confined to small groups of researchers studying the effects of single nutrients — such as particular vitamins or proteins — on a few dozen volunteers, is now adopting the heavy-lifting tools developed for genetics and pharmaceutical research. It also has a catchy name: nutrigenomics. And the more that researchers learn how our genes interact with our diet, the more they appreciate the deeper insight gained by an interdisciplinary approach. Such knowledge could lead to breakthroughs in our understanding of risk factors for diabetes and cardiovascular disease or, for example, improve the design of weight-loss diets.

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Winter in the Picos de Europa

CUMC2010coverfrontThe snow under my tentatively placed left boot gave way and I scampered back onto my perch. I leaned heavily on my ice axe with one hand and cheerlessly on the snow with my other hand. I pawed the snowy slope like a misguided rhinoceros charging up the wrong mountain. When I hazarded a look at my leg, I noted a dismaying gap between its boot and crampon. Continue reading Winter in the Picos de Europa