Researchers have devised a treatment that mechanically repairs burst cell membranes in the brain, somewhat like puncture sealants used in bicycle tyres, and could therefore help to avert brain damage after serious head injuries.
Brain-injured rats that are injected with a polymer called polyethylene glycol (PEG) soon after their injuries recover certain behavioural abilities better than untreated rats, report researchers in this week’s Journal of Biological Engineering. Continue reading Cellular ‘puncture repair kit’ may minimize brain trauma→
Tony Kouzarides tells the story of his early career as a comedy of errors. He started his Ph.D. at the University of Cambridge in the U.K. in 1981 studying the cancer-inducing potential of human cytomegalovirus. After a year of inserting part of the virus’s DNA into target cells, the cells showed almost no signs of cancer. He couldn’t rule out that other parts of the virus might do it, but he also couldn’t publish his early results. What he could publish by the end had more to do with genetic sequencing, an area he did not want to pursue.
After a short postdoc at Cambridge sequencing cytomegalovirus, he landed a second postdoc in a lab in New York studying oncogenes. There, he spent 2 years developing an unconfirmed and unpublishable hunch. On the strength of that record, he deadpans, he unsuccessfully applied to lead his own research group.
Mice with specific light-sensing cells removed from their retinas can see perfectly well but can’t tune their body clock, scientists have shown. The discovery provides more evidence that light detection by the retina is crucial for mammals to stay on a 24-hour circadian cycle. Continue reading Eye-damaged mice lose sight of the time→
Originally started by physicists of various obscure stripes, job-rumor Web sites now cover more than a dozen disciplines from anthropology to zoology. Some of these Web sites have a Webmaster who (sometimes) vets and posts rumors about postdoc and faculty jobs, whereas other sites take the form of wikis, which individual users can update. The sites offer varying levels of information, but all of them make water-cooler job rumors available to the world.