Tony Kouzarides tells the story of his early career as a comedy of errors. He started his Ph.D. at the University of Cambridge in the U.K. in 1981 studying the cancer-inducing potential of human cytomegalovirus. After a year of inserting part of the virus’s DNA into target cells, the cells showed almost no signs of cancer. He couldn’t rule out that other parts of the virus might do it, but he also couldn’t publish his early results. What he could publish by the end had more to do with genetic sequencing, an area he did not want to pursue.
After a short postdoc at Cambridge sequencing cytomegalovirus, he landed a second postdoc in a lab in New York studying oncogenes. There, he spent 2 years developing an unconfirmed and unpublishable hunch. On the strength of that record, he deadpans, he unsuccessfully applied to lead his own research group.
Mice with specific light-sensing cells removed from their retinas can see perfectly well but can’t tune their body clock, scientists have shown. The discovery provides more evidence that light detection by the retina is crucial for mammals to stay on a 24-hour circadian cycle. Continue reading
Originally started by physicists of various obscure stripes, job-rumor Web sites now cover more than a dozen disciplines from anthropology to zoology. Some of these Web sites have a Webmaster who (sometimes) vets and posts rumors about postdoc and faculty jobs, whereas other sites take the form of wikis, which individual users can update. The sites offer varying levels of information, but all of them make water-cooler job rumors available to the world.
Buddhist artists in Bamiyan, Afghanistan, may have painted with oils centuries before European Renaissance painters developed the technique.
A team led by Marine Cotte at the European Synchrotron Radiation Facility in Grenoble, France, has analyzed tiny samples of paintings sent by a UNESCO conservation team from a site where the Taliban destroyed two giant Buddha statues in 2001. Initial scans with ultraviolet light led researchers to suspect the presence of oil, and “we have confirmed it,” says Cotte. Twelve of 50 murals depicting colorful Buddhas and mythical creatures, painted in caves behind the statue niches, included pigments bound in plant oils. Oil offers “more freedom” to artists, says Cotte, as it doesn’t set instantly like the gypsum or calcium salt pigments also used in the caves.
Helen Howard of the National Gallery in London says European oil paintings date back to the 12th century, but whether oil was used earlier isn’t known because “analysis hasn’t often been carried out on very early paintings.” UNESCO team leader Yoko Taniguchi of the National Research Institute for Cultural Properties in Tokyo said in a statement that ancient Romans and Egyptians were known to use drying oils, but only as medicines and cosmetics. Thus, the team writes in April’s Journal of Analytical Atomic Spectrometry, the Afghan samples could be the “oldest example of oil paintings on Earth.”
Originally appeared in Science Magazine as a Random Sample: [html] [pdf]