Global health officials are intensifying efforts to eradicate yaws, a disfiguring skin disease that infects more than 64,000 people a year in 14 African and southeast Asian countries. But some critics say that the plans could fail, because they don’t take account of discoveries in the past few years that wild primate populations harbour the bacterial infection. That could complicate or foil eradication efforts, they say.
Public-health officials met in Geneva, Switzerland, on 29–30 January to discuss how to expand the eradication programme in 6 of the 14 countries in which yaws is endemic. But they did not discuss the part played by wild animals. “Even if this is not the main cause of re-emerging yaws nowadays, it would jeopardize global eradication,” says Sascha Knauf, who studies neglected tropical diseases at the Leibniz Institute for Primate Research in Göttingen, Germany. Continue reading →
Immunotherapy, which involves adapting immune cells to destroy specific cellular targets, has made a name for itself treating cancer. But over the last few years, a handful of research groups have advanced T-cell therapies for viral infections, and are now on the cusp of commercialization. “Using T cells to target infectious diseases is not a new field,” says immunologist Michael Keller of Children’s National Hospital in Washington, D.C., “but it’s something that’s expanding a great deal.” Continue reading →
When pharmacologist Ravindra Ghooi learned in 1996 that his mother had terminal breast cancer, he began to investigate whether he could obtain morphine, in case she needed pain relief at the end of her life. But a morphine prescription in India at that time, even for the dying, was a rare thing: most states required four or five different licences to buy painkillers such as morphine, and there were harsh penalties for minor administrative errors. Few pharmacies stocked opioids and it was a rare doctor who held the necessary paperwork to prescribe them. Ghooi, who is now a consultant at Cipla Palliative Care and Training Centre in Pune, used his connections to ask government and industry officials if there was a straightforward way of obtaining morphine for his mother. “Everybody agreed to give me morphine,” he recalls, “but they said they’d give it to me illegally.” Continue reading →
Journalist covering global development by way of science and technology.